Posts Tagged ‘PYC’

ASX Company News: Phylogica Granted Australian Patent

Friday, April 27th, 2012

Phylogica Ltd (PYC), a leading Australian peptide drug discovery company, announced  that it has been granted a new patent by the Australian Patent Office. This worldwide patent is pending in multiple other jurisdictions, including the USA, Europe and Japan. The patent covers methods of producing designed, synthetic libraries of peptides that are predicted to be rich in structure and, therefore, more likely to be drug-like than conventional random peptides.

Dr Paul Watt, Phylogica’s Chief Executive Officer, commented on the news: “The allowance of this patent adds another powerful component to Phylogica’s Phylomer platform and opens up new opportunities in the emerging field of synthetic biology. This patent further strengthens our core IP portfolio, which already includes multiple granted worldwide patents. It maintains Phylogica’s dominant intellectual property position over the construction and screening of the world’s most structurally diverse source of peptides.”

Phylogica Limited (PYC) is a biotechnology company based in Perth, Australia, and the UK, with a world-class drug discovery platform harnessing the rich biodiversity of nature to discover novel peptide therapeutics.

www.phylogica.com

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ASX Company News: Phylogica Granted US Patent For Stroke Treatment

Friday, February 24th, 2012

Phylogica Ltd (PYC), a leading Australian peptide drug discovery company, announced that it has been granted a new US Patent (Patent no. 8063012) entitled: ‘Neuroprotective peptide inhibitors of AP-1 signalling and uses thereof’ (derived from international patent application PCT/AU2007/000092). This patent covers a new Phylomer peptide, PYC38, and its derivatives, which show potent rescue from death of brain cells in models of neuronal death associated with conditions such as stroke and traumatic brain injury.

Phylogica’s CEO Dr Paul Watt said: “We are very pleased to have been granted this patent as it provides further validation of the biological activity of Phylomers against intracellular targets. This is important because Phylogica is rapidly establishing itself as a leader in the new frontier of identifying peptides, which not only get into cells, but also exert therapeutically relevant effects against targets within cells. About half of the discovery alliances that we are currently negotiating with the pharmaceutical and biotechnology industry are around the intracellular space.” Dr Watt continued: “The vast majority of therapeutic targets are found within cells, yet most of these targets are not tractable with conventional drugs such as small molecules.

Phylogica Limited (PYC) is a biotechnology company based in Perth, Australia, and Oxford, UK, with a world-class drug discovery platform harnessing the rich biodiversity of nature to discover novel peptide therapeutics. The Company was incorporated in 2001 as a spin out from the Telethon Institute for Child Health Research (Perth, Australia) and the Fox Chase Cancer Centre (Philadelphia, USA). The Company’s drug discovery platform is based on its proprietary Phylomer® libraries of natural peptides, which have been optimised by evolutionary selection to have stable drug-like structures. Phylogica offers fully integrated drug discovery services to the pharmaceutical industry utilising its Phylomer® libraries and proprietary screening technologies. Its current partners include Roche, MedImmune (AstraZeneca), Pfizer and Janssen Biotech (Johnson & Johnson).

www.phylogica.com

http://www.traderdealer.com.au/fundamentals/pyc

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ASX Company News: Phylogica Enters JV Agreement With Pfizer

Tuesday, December 21st, 2010

Phylogica Ltd (PYC), a public Australian drug discovery company, announced today that it has entered into a collaboration and licensing agreement with Pfizer to discover novel peptide-based vaccines. Phylogica will employ its proprietary Phylomer® drug discovery platform to identify Phylomer peptides suitable for further evaluation. Under the agreement, Phylogica grants Pfizer certain rights, including an option to license any resulting Phylomers for further research, development and commercialisation of novel peptide-based vaccines derived from such Phylomers. Under the terms of the agreement, Phylogica will receive an upfront payment of US$500,000. In addition, Phylogica is eligible to receive a commercial license payment and is also eligible to receive preclinical, clinical and other milestone payments of up to US$134 million, as well as royalties on worldwide sales.

Dr Paul Watt, the founder and CEO of Phylogica said: “We are delighted to be working with Pfizer. This alliance supports the potential utility of Phylogica’s Phylomer drug discovery platform for peptide-based drug discovery. With the present announcement, Phylogica has now entered into three alliances with global pharmaceutical companies within the last 12 months.”

Phylogica Limited (PYC) is biotechnology company based in Perth, Australia and Oxford UK, with a world-class drug discovery platform harnessing the rich biodiversity of nature to discover novel peptide therapeutics. Phylogica’s strategy is to accelerate cash sustainability by focusing on collaborative drug discovery partnerships. The Company’s Phylomer® libraries have been optimised by natural evolutionary selection for peptides with stable drug-like structures.

www.phylogica.com

http://www.traderdealer.com.au/Fundamentals/pyc

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