Posts Tagged ‘Cancer treatment’

ASX Company News: Novogen Secures Cancer Treatment Patent

Thursday, December 22nd, 2011

Novogen (NRT) subsidiary, Marshall Edwards, Inc., an oncology company focused on the clinical development of novel therapeutics targeting cancer metabolism, announced today that the US Patent and Trademark Office has issued a new patent covering a number of the company’s isoflavone-based compounds, including lead oncology drug candidates ME-143 and ME-344, and their pharmaceutical compositions. The patent is estimated to provide protection until March 2027.

“This patent represents another important milestone in our efforts to develop our lead drug candidates into valuable treatment options for patients with cancer” said Daniel P Gold, PhD, President and Chief Executive Officer of Marshall Edwards. “Furthermore, this demonstrates our commitment to further strengthening the intellectual property portfolio we acquired earlier this year, which will be essential for partnering any of our drug candidates and enhancing shareholder value.”

Marshall Edwards completed the acquisition of its isoflavone-based intellectual property portfolio, including worldwide rights to lead oncology drug candidates ME-143 and ME-344, from Novogen Limited in May 2011. The portfolio now includes 11 issued US patents, at least 14 US patent applications, at least 40 issued foreign patents and at least 80 foreign patent applications. Marshall Edwards, Inc. is a San Diego-based oncology company focused on the clinical development of novel anti-cancer therapeutics. The company’s lead programs focus on two families of small molecules that result in the inhibition of tumour cell metabolism. Novogen Limited (NRT) is an Australian biotechnology company based in Sydney, Australia. Novogen conducts research and development on oncology therapeutics through its subsidiary, Marshall Edwards, Inc., and is developing glucan technology through its subsidiary, Glycotex, Inc.

www.novogen.com

http://www.traderdealer.com.au/Fundamentals/nrt

Post to Twitter

ASX Company News: Viralytics Granted US Cancer Treatment Patent

Monday, November 28th, 2011

Viralytics Ltd (VLA) is pleased to announce the granting of a notice of allowance by the United States Patent and Trademark Office for issuance of a patent covering a Coxsackie A virus capable of infecting cancer cells substantially in the absence of intercellular adhesion molecule-1 (ICAM-1).  Dr Darren Shafren, Viralytics Chief Scientific Officer said “CAVATAK  targets and destroys cancerous cells following binding to surface expressed ICAM-1. The generation of this novel Coxsackie A virus, that can infect cancer cells in the absence of ICAM-1 expands the range of cancers that Viralytics panel of oncolytic viruses can potentially target”.

The scope of the allowed claims of US 10/592,395 covers a bio-selected form of Coxsackievirus A21 which was generated following passage in cells not expressing ICAM-1 but expressing decay accelerating factor (DAF). Decay accelerating factor expression is up-regulated on the surface of many cancerous cells including ovarian, colo-rectal and gastric cancers, making it a target for the newly bio-selected Coxsackievirus A21. The allowed claims also cover specific changes induced on the surface of the Coxsackievirus A21 during the bio-selection process on DAF-expressing cancer cells that are believed to confer the extended scope of cancer cell targeting.

www.viralytics.com

http://www.traderdealer.com.au/fundamentals/vla

Post to Twitter

ASX Company News: Antisense Therapeutics Granted Japanese Patent

Wednesday, July 13th, 2011

Antisense Therapeutics (ANP) is pleased to report the granting of Japanese patent No. 4753863 which covers the Company’s second generation antisense drug ATL1101 that targets the insulin-like growth factor I receptor (IGF-1R) and has potential applications in the treatment of cancer. At the same time, the Company also advises that it has received a Notice of Allowance on ATL1101 Canadian patent application 2515484 which will proceed to grant in the coming months. Both the Japanese and Canadian patents are entitled “Modulation of Insulin Like Growth Factor I Receptor Expression” and protect the use of ATL1101 until 2024. The Japanese and Canadian patents form part of the extensive portfolio of intellectual property protecting ATL1101 and its applications in the treatment of cancer. The Intellectual Property that is in place to support the successful development and commercialization of ATL1101 is an integral part of the value created by the Company.

Antisense Therapeutics Limited (ANP) is an Australian publicly listed biopharmaceutical drug discovery and development company. Its mission is to create, develop and commercialise antisense pharmaceuticals for large unmet markets. ANP has two drugs in development and two drugs in pre-clinical research. ATL1102 (injection) has successfully completed a Phase II efficacy and safety trial, significantly reducing the number of MRI lesions in patients with multiple sclerosis.

www.antisense.com.au

http://www.traderdealer.com.au/fundamentals/anp

Post to Twitter

Viralytics Secures Cancer Treatment Patent

Tuesday, March 31st, 2009

Viralytics Limited (VLA) has been granted a key patent by US authorities covering the use of Echoviruses for the treatment of all cancers expressing the integrin a2b1 molecule. EVATAK™ is the trade name for Viralytics’ proprietary formulation of the Echovirus Type 1. EV1 attach to the outside of cells, using a specific ‘receptor’ on the cell’s surface (like a key fitting a lock). EV1 uses the receptor, integrin a2b1 to bind and infect target cells. Types of cancer cells that express high levels of the integrin a2b1 molecule on their surface include ovarian, prostate and gastric cancers. Professor Darren Shafren (Chief Scientific Officer and inventor of the technology) said, “The granting of this US patent significantly increases Viralytics’ intellectual property portfolio, which already includes both US and European patents for a subset of Coxsackie A group viruses including CAVATAKTM, our lead product.” 

http://www.viralytics.com/

Post to Twitter

Prima BioMed Receives Patent for Ovarian Cancer Treatment

Friday, March 27th, 2009

Prima BioMed (ASX:PRR) announced that its subsidiary company, Cancer Vac Pty Ltd, has today been granted a patent covering the administration of Prima’s ovarian cancer immunotherapy product CVacTM by the European Patent Office. CVac™ is Prima BioMed’s lead product. It is a therapy treatment for ovarian cancer administered post-surgery and post-chemotherapy to delay relapse and control metastases.

There is a large un-met medical need for new treatments for ovarian cancer which has a very high morbidity rate, and currently there are no maintenance based therapy products commercially available. The Company is making rapid progress towards commercializing CVac™ into the global multi-billion oncology pharmacy market.

http://www.primabiomed.com.au

Post to Twitter